SARS-CoV-2 and Cancer Vaccine
Platforms in Development
BioVaxys is a clinical-stage biopharma developing antiviral & anticancer vaccine platforms. The Company is evaluating a potential SARS-CoV-2 vaccine based on its haptenized viral protein technology, and advancing a compassionate use trial in the EU to evaluate its haptenized cell vaccine for late-stage ovarian cancer.
T-Cell Antigen Discovery Program
In addition to our haptenized cell vaccines for ovarian cancer and other tumor types, we are exploring ways we can leverage our technology platform in the field of Adoptive Immunotherapy, which is also of significant interest in the immune-oncology market. Adoptive Immunotherapy is where T-cells are collected from a patient and grown in the laboratory. This increases the number of T-cells that are able to kill cancer cells.
Our ovarian cancer clinical studies and manufacturing protocol will provide us with the unique ability to collect T-cells from patients, both pre- and post- vaccine administration. BioVaxys’ objective is to use T-cells made responsive to it’s vaccines to identify new antigens that can be synthesized and explored, as they may prove useful as diagnostic agents or as new, chemically-defined, patient-specific vaccines. These novel antigens may be distinct for each patient, or present across all tumor cells. BioVaxys intends to explore partnerships with CAR T/TCR cell therapy companies to identify novel cancer antigens eliciting a T-cell response, which will develop extensive new intellectual property for BioVaxys.
Our Intellectual Property
Exclusive license from Thomas Jefferson University for patents related to haptenized cancer vaccines
Three patent applications based on internal discoveries for a bihaptenized cancer vaccine platform in combination with checkpoint inhibitors
Patent application based on internal discoveries related to a haptenized viral antigen vaccines platform.
Executive Team & Board
Founder, Chief Executive Officer and Director
Mr. James Passin is a former hedge fund and private equity fund manager at FGS Advisors, LLC, an affiliate of New York-based Firebird Management LLC. He has 20 years of experience as a professional investor, a deep experience of financing and developing venture-stage companies, and directed and managed over $155 million of equity and debt investment into biotech companies including Avax Technologies, Inc., one of the world’s first cellular immunotherapeutic vaccine companies. He is a director of several public companies, including TraceSafe Inc. (CSE: TSF) and BDSec JSC (MSE: BDS), is a Chartered Market Technician and member of the CMT Association..
Founder, President and Chief Operating Officer
Mr. Kovan has over 30 years of experience in biopharmaceuticals commercial development. He recently served as Corporate Development Partner with Horizon Discovery plc in the United Kingdom, and is Managing Principal & Owner of Bingham Hill Ventures, a life sciences advisory practice he founded in 2012 that specializes in corporate development, technology licensing, and business planning. He is an experienced former biotech CEO and board member, and founder of biotechnology companies including the former Avax Technologies, Inc. Mr. Kovan’s professional background includes several years in technology transfer with Thomas Jefferson University, Strategic Marketing with GlaxoSmithKline, and Global New Product Development with Wyeth-Ayerst Pharmaceuticals. His therapeutic experience includes infectious disease, antivirals, oncology, vaccines, cell/gene therapy, and gene editing. Mr. Kovan has a broad international business background, having launched pharma brands in Latin American and Asia/Pacific markets, and has worked in Europe for several years.
David Berd, M.D.
Founder and Chief Medical Officer
Dr. David Berd is a medical oncologist with a lifelong record of clinical research in medical oncology and cancer immunotherapy. He cofounded cancer immunotherapy company AVAX Technologies, is the inventor of the cancer vaccines MVax™ and OVax™, and served as Chief Medical Officer 2005-2008. As National Director for Immunotherapy at Cancer Treatment Centers of America, Dr. Berd investigated the application of the AC vaccine to ovarian cancer. Previously, Dr. Berd was Professor of Medicine at Thomas Jefferson University, where for 20 years he conducted clinical research on melanoma immunotherapy. He also spent nine years as a research physician at Fox Chase Cancer Center. Over the course of his career, Dr. Berd has published more than 85 original papers in numerous medical journals alongside dozens of editorials, reviews and abstracts. He has ten issued patents dealing with cancer vaccines. Throughout his career, he has participated in national and international conferences on melanoma and cancer immunotherapy. Dr. Berd received his BS from Pennsylvania State University and his MD from Jefferson Medical College of Thomas Jefferson University.
Lachlan McLeod, CPA
Chief Financial Officer
Mr. Lachlan McLeod, a Chartered Professional Accountant, holds a Bachelor’s Degree in Science with an Economics major and a Business minor from the University of Victoria. He has 6 years of experience focusing on financial reporting under IFRS, governance for public companies, and technical accounting issues, including work as an auditor at KPMG. Mr. McLeod currently works as a Senior Consultant at Fehr & Associates CPA, which provides external consulting and accounting services.
• 15+ years experience in the capital markets
• Co-founder, former director & officer of Pure Energy Minerals Limited
• Former CEO of Bearing Lithium (CSE: BLILF); Led transformation of the company through the acquisition of Li3 Energy and facilitated a number of over-subscribed capital raises.
• Strong network of investor and industry contacts, served on a number of boards, and held senior officer positions at several public and private companies
William Timothy Heenan
Mr. Heenan is a founder of Mirasol Resources Ltd. and a former director of Mirasol for over 12 years since its inception and listing on the TSX Venture Exchange. He has been based in Mendoza, Argentina with Mirasol as Exploration Manager since its inception in 2003, and prior to that lived in Chile and worked for numerous mining and exploration companies in Chile for over a decade.
From his tenure as a director, Mr. Heenan has become experienced with legal, corporate and administrative matters, is fluent in Spanish, and has developed an extensive network of contacts. A Canadian citizen by birth, he maintains definitive legal residency status in both Chile and Argentina. He is also a director of Bearing Lithium Corp., a public company listed on the TSX Venture Exchange. Mr. Heenan obtained a Bachelor of Science from the University of Regina in 1987.